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S1)." Excerpts from page 16223: "The higher diversity in the AJ population was paralleled by a lower inbreeding coefficient, F, indicating the AJ population is more outbred than Europeans, not inbred, as has long been assumed (P "Through genomic analysis, researchers at Emory University School of Medicine have shown that the Ashkenazi Jewish population is genetically more diverse than people of European descent, despite previous assumptions that Ashkenazi Jews have been an isolated population.
In addition, analyses of disease-related genes of higher prevalence in the Ashkenazi Jewish population indicate that only a minority of traits show signs of positive selection, suggesting that most have arisen through random genetic drift.
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Recent reports have reaffirmed that the AJ population has a common Middle Eastern origin with other Jewish Diaspora populations, but also suggest that the AJ population, compared with other Jews, has had the most European admixture.
Our analysis indeed revealed higher European admixture than predicted from previous Y-chromosome analyses.
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